Thermo Fisher Scientific PSMB4 Monoclonal Antibody (OTI2C9), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:150

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure composed of 4 rings of 28 non-identical subunits—2 rings of 7 alpha subunits and 2 rings of 7 beta subunits. Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal process.
A modified proteasome, the immunoproteasome, processes class I MHC peptides. The PSMB4 gene encodes a member of the proteasome B-type (T1B) family, a 20S core beta subunit.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.