Thermo Fisher Scientific CYP2A6/CYP2A7/CYP2A13 Polyclonal Antibody
인간 CYP2A6, CYP2A7, CYP2A13 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 적합합니다. 비결합형 액상 형태이며 1 mg/mL 농도로 제공됩니다. -20°C 보관, Wet ice 배송 조건. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific CYP2A6/CYP2A7/CYP2A13 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human CYP2A6/CYP2A7/CYP2A13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691469 |
Target Information
The cytochrome P450 (P450) superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several co-factors such as nicotinamide adenine dinucleotide phosphate (NADPH) and P450 reductase.
There are over 200 known genes which encode P450s. Epoxygenases metabolize AA to epoxyeicosatrienoic acids (EETs), and omega-hydroxylases produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE).
In addition to fatty acid metabolism, P450s also metabolize many drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids, and rifampicin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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