Thermo Fisher Scientific CHD9 Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:2,000

Product Specifications

Product Specific Information

The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is greater than 95% (by SDS-PAGE).

Target Information

CHD9 (chromodomain-helicase-DNA-binding protein 9), also known as chromatin-related mesenchymal modulator (CReMM), PPAR-α-interacting complex protein, kismet homolog 2, or CHROM1, is a 2,897 amino acid protein belonging to the Snf2/Rad54 helicase family.
The CHD family of proteins are ATP-dependent chromatin remodeling enzymes that combine chromodomains with SWI2/Snf2 ATPase/helicase motifs and DNA-binding capability.
CHD9 localizes to both the cytoplasm and nucleus and contains two chromodomains, one ATP-binding helicase domain, and one C-terminal helicase domain. Chromodomains are highly conserved regions (~40–50 amino acids) found in chromatin-associated proteins across plants and animals.
CHD9 acts as a transcriptional coactivator for PPARα and may function as an ATP-dependent chromatin remodeling protein. It is widely expressed at low levels and exists in three isoforms produced by alternative splicing.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.