Thermo Fisher Scientific PARN Polyclonal Antibody
PARN 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot 및 IHC(P)에서 검증되었으며, 항원 친화 크로마토그래피로 정제되었습니다. 4°C 단기 보관, -20°C 장기 보관 권장.
- 카탈로그번호
- PA552280
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PARN. Recombinant protein control fragment (Product # RP-89279) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645212 |
Product Specific Information
Immunogen sequence:
DGEFSGISDG PSVSALTNGF DTPEERYQKL KKHSMDFLLF QFGLCTFKYD YTDSKYITKS FNFYVFPKPF NRSSPDVKFV CQSSSIDFLA SQGFDFNKVF RNGIPYLNQE EERQLREQYD EKRSQANGAG A
Highest antigen sequence identity to orthologs:
- Mouse: 92%
- Rat: 91%
Target Information
The protein encoded by this gene is a 3′-exoribonuclease, similar to the RNase D family of 3′-exonucleases. It preferentially degrades poly(A) tails of mRNAs, initiating mRNA decay in eukaryotes. This protein also participates in silencing of maternal mRNAs during oocyte maturation and early embryonic development, and in nonsense-mediated decay (NMD) of mRNAs with premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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