Thermo Fisher Scientific Human ACVRL1 (ALK1), GST Tag Recombinant Protein
Human ACVRL1 (ALK1) 단백질을 GST 태그로 발현한 재조합 단백질로, TGF-β 수용체 연구용으로 적합함. Insect cell 시스템에서 생산되었으며, 고순도 정제된 액상 형태. -80°C에서 보관하며 kinase assay 등 연구용으로 사용 가능.
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Thermo Fisher Scientific Human ACVRL1 (ALK1), GST Tag Recombinant Protein
Applications
- Kinase Assay (KA)
Tested Dilution
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | Insect cells |
| Amino Acid Sequence | 139–503 |
| Tag | GST-tag |
| Molecular Weight | 68.9 kDa |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Purified |
| Storage Buffer | 50 mM Tris (pH 7.5), 150 mM NaCl, 0.5 mM EDTA, 0.02% polysorbate 20, 50% glycerol, 2 mM DTT |
| Contains | No preservative |
| Storage Conditions | -80°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
Product Specific Information
- For maximum recovery, please spin prior to use.
- Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use material in original packaging until exhausted.
- For larger sizes, reduce freeze/thaw cycles by preparing aliquots (not below 20 µL).
- Do not store diluted kinase.
- Properly stored at -80°C, product guaranteed for 6 months from date of purchase.
- Protein Form: Catalytic
Target Information
Activin A receptor type II-like 1 (ACVRL1) is a type I cell-surface receptor of the TGF-β superfamily. It contains a conserved serine-threonine kinase subdomain, a glycine- and serine-rich GS domain, and a short C-terminal tail.
Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2 and have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by abnormal bone formation in soft tissues, as well as Epicanthus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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