Thermo Fisher Scientific PMS1 Polyclonal Antibody
PMS1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human 시료에 반응합니다. Western Blot 및 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. DNA mismatch repair 연구 및 Lynch syndrome 관련 연구에 유용합니다.
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Thermo Fisher Scientific PMS1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunoprecipitation (IP) | 1:100–1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 288–545 of PMS1 (UniProt ID: P54277-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at −20°C, avoiding freeze/thaw cycles. |
| RRID | AB_2553262 |
Product Specific Information
- Recommended positive controls: 293T, A431, HeLa, HepG2
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
PMS1 encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein participates in the repair of DNA mismatches and forms heterodimers with MLH1, another mismatch repair protein. Mutations in PMS1 are associated with hereditary nonpolyposis colorectal cancer type 3 (HNPCC3), also known as Lynch syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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