Thermo Fisher Scientific MYBPC3 Polyclonal Antibody
인간 MYBPC3 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:500~1:1,000 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 버퍼에 보존. 심근 단백질 연구 및 심근병 관련 연구용에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MYBPC3. Recombinant protein control fragment: Product #RP-97333 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2790842 |
Product Specific Information
Immunogen sequence:
TGDSDEWVFD KKLLCETEGR VRVETTKDRS IFTVEGAEKE DEGVYTVTVK NPVGEDQVNL TVKVIDVPDA
Target Information
Myosin binding protein C, cardiac-type (MYBPC3) is a thick filament-associated protein located in the crossbridge region of vertebrate striated muscle A bands.
In vitro, it binds MHC, F-actin, and native thin filaments. It modifies the activity of actin-activated myosin ATPase and may modulate muscle contraction or play a structural role.
Mutations in the gene can result in:
- Cardiomyopathy, familial hypertrophic 4
- Cardiomyopathy, dilated 1MM
- Left ventricular non-compaction 10
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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