Thermo Fisher Scientific SAPAP4 Polyclonal Antibody
Human SAPAP4 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 검증 완료. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol) buffer에 보관. 연구용으로 신경 시냅스 단백질 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SAPAP4. Recombinant protein control fragment (Product #RP-99293). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646943 |
Product Specific Information
Immunogen sequence:
GVQVEDDWRS SVPSHSMSSR RDTDSDTQDA NDSSCKSSER SLPDCTPHPN SISIDAGPRQ APKIAQIKRN LSYGDNSDPA L
Highest antigen sequence identity to orthologs:
- Mouse: 96%
- Rat: 98%
Target Information
SAP90/PSD-95-associated protein 4 (SAPAP4, also known as DLGAP4) is a member of a protein family that specifically interacts with PSD-95/SAP90, a membrane-associated guanylate kinase localized at the postsynaptic density (PSD) in neuronal cells. Like other SAPAP proteins, SAPAP4 acts as an adaptor protein interacting with various synaptic scaffolding proteins, cytoskeletal, and signaling components such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP4 mRNA is targeted to cell bodies similarly to SAPAP1 and -2, while SAPAP3 mRNA is mainly detected in cell bodies.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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