Thermo Fisher Scientific GSK-3 Beta CT Polyclonal Antibody
다양한 응용 분야(WB, IHC, ICC, Flow, ELISA)에 적합한 GSK-3 Beta 폴리클로날 항체. 사람, 생쥐, 랫트 반응성. 고순도 Protein A 정제, 액상 형태로 제공. 에너지 대사 및 Wnt 신호 조절 연구에 활용 가능.
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Thermo Fisher Scientific GSK-3 Beta CT Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| Flow Cytometry (Flow) | 1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human GSK-3 Beta, amino acids 341–420 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
GSK3B is a proline-directed serine/threonine protein kinase involved in energy metabolism, neuronal cell development, and body pattern formation. It negatively regulates glucose homeostasis and participates in inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways.
GSK3B is a key component of the Wnt/beta-catenin signaling pathway, mediating beta-catenin degradation and inhibiting Wnt signaling. It is also involved in Hedgehog, Notch, and insulin signaling pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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