Thermo Fisher Scientific CD4 Monoclonal Antibody (OTI7G9), TrueMAB
인간 CD4 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB와 IHC(P) 실험에 적합합니다. TrueMAB 포맷으로 고순도 정제되어 안정적인 신호를 제공합니다. 연구용으로만 사용되며, HIV 및 면역 관련 연구에 활용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7G9 |
| Immunogen | Full length human recombinant protein of human CD4 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV.
CD4 is primarily expressed in a subset of T-lymphocytes (T helper cells) and can also be found in monocytes, macrophages, and dendritic cells.
At the tissue level, CD4 expression occurs in thymus, lymph nodes, tonsils, spleen, and certain regions of the brain and gut.
CD4 contributes to T-cell activation via association with the T-cell receptor complex and protein tyrosine kinase Lck.
It may also mediate neuronal damage in infectious and immune-related diseases of the CNS.
Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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