Thermo Fisher Scientific CD16 Monoclonal Antibody (3G8), PE-Alexa Fluor 700
인간 CD16 단백질을 인식하는 마우스 모노클로날 항체로, PE-Alexa Fluor 700으로 결합되어 형광 분석에 적합합니다. Flow Cytometry에 사용되며, 정제된 액상 형태로 제공됩니다. 4°C에서 암소 보관하며, 다양한 형광 포맷으로도 이용 가능합니다.
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Applications
- Flow Cytometry (Flow): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3G8 |
| Immunogen | Human CD16 |
| Conjugate | PE-Alexa Fluor™ 700 |
| Excitation / Emission Max | 566 / 721 nm |
| Form | Liquid |
| Purification | Purified |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10373538 |
Additional Formats
- Alexa Fluor 700
- APC
- FITC
- Pacific Blue
- Pacific Orange
- PE
- PE-Texas Red
- PerCP
- Request custom conjugation
Target Information
CD16 encodes a receptor that recognizes the Fc portion of immunoglobulin G and is involved in the clearance of immune complexes from circulation, as well as in processes such as cell-mediated cytotoxicity and enhancement of viral infections. The gene FCGR3A shares high similarity with FCGR3B, located nearby on chromosome 1.
The receptor encoded by FCGR3A is expressed on natural killer (NK) cells as an integral membrane glycoprotein, while FCGR3B is expressed on polymorphonuclear neutrophils (PMN) and anchored through a phosphatidylinositol (PI) linkage.
Mutations in this gene are associated with Immunodeficiency 20, and linked to susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been identified.
Analyte Specific Reagent
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