Thermo Fisher Scientific CD1C Monoclonal Antibody (OTI1E10), TrueMAB
CD1C 단백질을 인식하는 마우스 단일클론 항체로, Western blot에 최적화됨. 인간 및 개 시료에 반응. 동결건조 형태로 제공되며 PBS 완충액에 트레할로스 포함. 연구용으로 세포 내 지질 항원 제시에 관련된 CD1C 단백질 연구에 적합.
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- CF505400
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- pk
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Applications
- Western Blot (WB): 1:200–1:4000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E10 |
| Immunogen | Full length human recombinant protein of human CD1C produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene encodes a member of the CD1 family of transmembrane glycoproteins, structurally related to MHC proteins, and forms heterodimers with beta-2-microglobulin. CD1 proteins mediate the presentation of lipid and glycolipid antigens to T cells.
The human genome contains five CD1 family genes on chromosome 1, differing in localization and lipid ligand specificity. The CD1C protein localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail and requires vesicular acidification for lipid antigen binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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