Thermo Fisher Scientific OAZ3 Polyclonal Antibody
OAZ3 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체로, Western blot에 적합합니다. 인간, 마우스, 랫트 시료에서 반응하며, 고순도 친화 크로마토그래피로 정제되었습니다. -20°C에서 보관하며 연구용으로 사용됩니다.
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Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human OAZ3 (Accession Q9UMX2), corresponding to amino acid residues E159–A209 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853323 |
Product Specific Information
Antibody detects endogenous levels of total OAZ3.
Target Information
The antizyme family is a group of small proteins that regulate cell growth and division by controlling the biosynthesis of polyamines such as putrescine, spermidine, and spermine.
OAZ3 (Ornithine decarboxylase antizyme 3) is a 187 amino acid protein belonging to the ODC antizyme family. It likely plays a key role in spermatogenesis by regulating intracellular polyamine concentrations in haploid germ cells through binding and destabilizing ornithine decarboxylase.
Mutations in the AZ3 gene are not a common cause of male infertility, and the normal AZ3 protein does not accelerate ornithine decarboxylase degradation. AZ3 expression begins sharply in early spermatids, peaks in later stages, and disappears in spermatozoa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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