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Thermo Fisher Scientific Phospho-BCAR1 (Tyr249) Polyclonal Antibody
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인간 BCAR1의 Tyr249 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, IHC, ICC/IF, ELISA 등에 사용 가능. Protein A로 정제된 액상 형태이며, 높은 특이성과 재현성을 제공. 연구용으로 세포 신호전달 및 인산화 경로 분석에 적합.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 05. 오후 04:12
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Thermo Fisher Scientific BS-12574R Phospho-BCAR1 (Tyr249) Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
569,000원VAT 포함 625,900원
Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-BCAR1 (Tyr249) Polyclonal Antibody
Thermo Fisher Scientific Phospho-BCAR1 (Tyr249) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human BCAR1 around the phosphorylation site of Tyr249 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signaling via v-Crk and v-Src oncoproteins. It possesses a unique structure containing an SH3 domain followed by multiple YXXP motifs and a proline-rich region. p130Cas is involved in various biological processes, including:
- Cell adhesion and migration
- Growth factor stimulation
- Cytokine receptor engagement
- Bacterial infection
Physiological functions include cardiovascular development, actin filament assembly, and Src-induced cell transformation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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