Thermo Fisher Scientific DPP10 Polyclonal Antibody
Rabbit polyclonal antibody against human DPP10 protein. Validated for IHC (Paraffin) at 10 µg/mL. Recognizes multiple species with high sequence identity. Suitable for research on asthma and DPP family proteins. For research use only.
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- PA533471
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- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested at 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Horse, Guinea pig, Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from internal region of human DPP10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550851 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- 100%: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Panda, Bovine, Dog, Horse, Guinea pig
- 94%: Galago, Bat, Rabbit, Pig
- 88%: Opossum, Turkey, Zebra finch, Chicken, Xenopus
- 82%: Mouse, Rat, Hamster, Elephant
Note: Proteinase K is required for antigen retrieval.
Target Information
The DPP10 gene encodes a homolog of dipeptidyl peptidases (DPPs) that cleave terminal dipeptides from cytokines and chemokines, representing a potential target for asthma therapy. DPP10 shares structural features with the S9B family of DPP serine proteases, including DPP4, which plays a key role in chemokine processing within the innate immune system. The gene locus exhibits complex transcript splicing patterns, with eight alternate first exons, four of which are located within the LD block associated with asthma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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