Thermo Fisher Scientific PRTN3 Monoclonal Antibody (OTI5B8), TrueMAB
인간 PRTN3 단백질을 표적으로 하는 마우스 단클론 항체로, IHC(P) 적용에 적합합니다. TrueMAB 형식의 고순도 항체이며, 무보존제 PBS 버퍼에 동결건조 상태로 제공됩니다. 연구용으로만 사용 가능하며, 재구성 및 결합 실험에 용이합니다.
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Thermo Fisher Scientific PRTN3 Monoclonal Antibody (OTI5B8), TrueMAB
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5B8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 28–248 of human PRTN3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) ([PubMed:3198760], [PubMed:2033050], [PubMed:28240246]).
By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and vascular integrity during neutrophil transendothelial migration ([PubMed:23202369]).
May play a role in neutrophil transendothelial migration, possibly when associated with CD177 ([PubMed:22266279]).
[UniProt]
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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