Thermo Fisher Scientific OSGEP Polyclonal Antibody
Thermo Fisher Scientific의 OSGEP 폴리클로날 항체로, 인간 단백질에 반응하며 ICC/IF에 사용 가능. Recombinant Protein Epitope Signature Tag 기반 항원으로 제작. 액상 형태이며 0.05 mg/mL 농도, 친화 크로마토그래피로 정제됨. 연구용으로만 사용.
- 카탈로그번호
- PA5144786
- 판매단위
- pk
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Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 130–201). Recombinant protein control fragment (Product #RP-109968). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_3091829 |
Product Specific Information
- Immunogen sequence:
YVSGGNTQVI AYSEHRYRIF GETIDIAVGN CLDRFARVLK ISNDPSPGYN IEQMAKRGKK LVELPYTVKG MD - Antigen sequence identity: Mouse 99%; Rat 99%
Target Information
Osgep (O-sialoglycoprotein endopeptidase), also known as GCPL1, is a 335 amino acid protein that belongs to the peptidase M22 family. It specifically cleaves the 31-Arg-l-Asp-32 bond in glycophorin A, but does not cleave desialylated glycoproteins, unglycosylated proteins, or glycoproteins that are only N-glycosylated.
Though expressed at low levels ubiquitously, the highest expression is found in liver, skeletal muscle, and kidney.
OSGEPL1 (Qri7) is a 414 amino acid protein in the KAE1/YgjD family, existing as three alternatively spliced isoforms. In tRNAs with codons beginning with adenine, OSGEPL1 is required for threonylcarbamoyl group formation on adenosine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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