Thermo Fisher Scientific ELOVL1 Polyclonal Antibody, Biotin
Thermo Fisher Scientific의 ELOVL1 Polyclonal Antibody, Biotin은 인간 및 비인간 영장류 시료에 반응하는 고품질 항체입니다. Western blot, IHC, ELISA, IP 등 다양한 응용에 적합하며, 합성 펩타이드 면역원 기반으로 제작되었습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- ELOVL1-BIOTIN
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 148–198 of human ELOVL1 |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Elongation of very long chain fatty acid-like (ELOVL) proteins 1–6 are members of the ELO family, which play a crucial role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids.
ELOVL proteins act as catalysts in fatty acid elongation and localize to the endoplasmic reticulum (ER).
ELOVL1, also known as Ssc1, is the human homolog of yeast ELO3 and is highly expressed in stomach, skin, intestine, kidney, and lung.
It participates in elongation of very long chain saturated and monounsaturated fatty acids (up to 26 carbons), contributing to epithelial barrier formation and myelin development in the CNS.
Impaired ELOVL1 activity may be associated with sphingolipid metabolism disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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