Thermo Fisher Scientific ALKBH3 Polyclonal Antibody
Rabbit에서 유래한 ALKBH3 폴리클로날 항체로, 인간 ALKBH3 단백질에 특이적입니다. 액상 형태로 제공되며, 0.1 mg/mL 농도입니다. DNA 복구 연구 및 단백질 발현 분석에 적합합니다. 연구용으로만 사용 가능합니다.
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ALKBH3 (amino acids 14–139) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage Conditions | Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637866 |
Product Specific Information
Immunogen sequence:
WAAPVKSQAI AQPATTAKSH LHQKPGQTWK NKEHHLSDRE FVFKEPQQVV RRAPEPRVID REGVYEISLS PTGVSRVCLY PGFVDVKEAD WILEQLCQDV PWKQRTGIRE DITYQQPRLT AWYGEL
Highest antigen sequence identity to the following orthologs:
- Mouse: 78%
- Rat: 79%
Target Information
Dioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate, and iron.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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