Thermo Fisher Scientific CST8 Polyclonal Antibody

Applications

Western Blot (WB)

• Assay-dependent

Immunohistochemistry (Paraffin) (IHC (P))

• Dilution: 1:500

Product Specifications

Target Information

The cystatin superfamily is a well-established family of cysteine protease inhibitors. All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, while some also inhibit legumain family enzymes.
The CRES (cystatin-related epididymal spermatogenic) protein defines a new subgroup in the family 2 cystatins of the cystatin superfamily. CRES proteins lack two of the three consensus sites necessary for the cystatin inhibition of C1 cysteine proteases. They are preferentially expressed in postmeiotic germ cells, the proximal caput epididymidis, and anterior pituitary gonadotrophs.
As a member of the CRES subfamily, Cystatin 8 is a 142 amino acid protein expressed in the proximal caput region of the epididymis, where it performs a specialized role during sperm development and maturation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.