Thermo Fisher Scientific Caspase 4 Polyclonal Antibody
Caspase 4 단백질을 인식하는 Thermo Fisher Scientific의 다클론 항체입니다. Western blot에 적합하며 인간 시료에 반응합니다. 합성 펩타이드 면역원으로 제작되었으며, 액상 형태로 제공되고 -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (CKERAEEIYPIKERN) corresponding to internal amino acids of CASP4 (aa 118–133) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10987547 |
Product Specific Information
- Predicted to react with bovine, canine, feline, and mouse based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 16,000.
Target Information
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase can cleave and activate its own precursor protein, as well as the caspase 1 precursor. When overexpressed, this gene induces apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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