Thermo Fisher Scientific MCM3 Monoclonal Antibody (1593CT377.41.73)
MCM3 단백질을 인식하는 Thermo Fisher Scientific의 마우스 단일클론 항체입니다. Western blot과 유세포분석에 사용 가능하며, 인간·생쥐·쥐 시료에 반응합니다. Protein G로 정제된 액상 형태로, 안정적인 저장 및 재현성 높은 결과를 제공합니다.
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Thermo Fisher Scientific MCM3 Monoclonal Antibody (1593CT377.41.73)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Flow Cytometry (Flow) | 1:25 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat, Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1593CT377.41.73 |
| Immunogen | Recombinant protein of human MCM3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897618 |
Target Information
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication.
The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins.
This protein is a subunit of the complex consisting of MCM2-7, and interacts directly with MCM5/CDC46.
It also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase.
The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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