Thermo Fisher Scientific IFNGR2 Polyclonal Antibody
인간 IFNGR2에 반응하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC(P) 및 ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 4°C 단기, -20°C 장기 보관. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human IFNGR2. Recombinant protein control fragment (Product #RP-95409) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2642643 |
Product Specific Information
- Immunogen sequence:
ASPSAGFPMD FNVTLRLRAE LGALHSAWVT MPWFQHYRNV TVGPPENIEV TPGEGSLIIR FSSPFDIADT STAFFCYYVH YWEKGGIQQV KGPFRSNSIS LDNLKPSRVY CLQVQAQLLW NKSNIFRVGH LSNIS - Highest antigen sequence identity to the following orthologs:
- Mouse: 57%
- Rat: 57%
Target Information
This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2.
Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection.
MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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