Thermo Fisher Scientific IFNGR2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human IFNGR2. Recombinant protein control fragment (Product #RP-95409). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IFNGR2,uniProtId:P38484-1,ncbiNodeId:9606,antigenRange:99-233,antigenLength:337,antigenImageFileName:PA5-51596_IFNGR2_P38484-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51596_IFNGR2_P38484-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642643

Product Specific Information

Immunogen sequence: ASPSAGFPMD FNVTLRLRAE LGALHSAWVT MPWFQHYRNV TVGPPENIEV TPGEGSLIIR FSSPFDIADT STAFFCYYVH YWEKGGIQQV KGPFRSNSIS LDNLKPSRVY CLQVQAQLLW NKSNIFRVGH LSNIS

Highest antigen sequence identity to the following orthologs: Mouse - 57%, Rat - 57%.

Target Information

This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.