
Thermo Fisher Scientific D2 Dopamine Receptor (extracellular) Polyclonal Antibody, FITC
FITC로 표지된 D2 도파민 수용체(Extracellular) 폴리클로날 항체로, 인간, 마우스, 랫트 시료에 반응합니다. Flow Cytometry에 적합하며, 고순도의 항원 친화 크로마토그래피로 정제되었습니다. -20°C 보관, 재구성 후 단기 4°C 보관 권장.
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Applications
- Flow Cytometry (Flow): 5 µg/0.5×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)DDLERQNWSRPFNGSE, corresponding to amino acid residues 11–26 of rat DRD2, Extracellular, N-terminus |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: 50 µL double distilled water (DDW), depending on sample size.
- The antibody ships as a lyophilized powder at room temperature.
- Upon arrival, store at -20°C.
- Reconstituted solution can be stored at 4°C for up to 1 week.
- For longer storage, aliquot and keep at -20°C.
- Avoid multiple freeze/thaw cycles.
- Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
The DRD2 Dopamine Receptor is involved in the neuromodulation of appetitive behaviors. DRD2 may be linked to alcoholism and other substance-use disorders. Mutations in DRD2 in mice lead to suppression of reward behavior with morphine and reduction of spontaneous movements, resembling Parkinson’s disease. Three alternatively spliced isoforms have been identified. DRD2 is expressed in various brain regions, as well as in aorta, artery, eye, and spinal cord. ESTs have been isolated from normal pituitary and in brain, colon, lung, pancreas, and skeletal muscle cancer libraries.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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