Thermo Fisher Scientific ALDH1B1 Polyclonal Antibody
Human ALDH1B1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC/IF에 적합. 고순도 항원 친화 크로마토그래피로 정제되었으며, PBS buffer와 glycerol 포함. 연구용으로만 사용.
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Thermo Fisher Scientific ALDH1B1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ALDH1B1. Recombinant protein control fragment (Product #RP-92988). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637840 |
Product Specific Information
- Immunogen sequence:
MLRFLAPRLL SLQGRTARYS SAAALPSPIL NPDIPYNQLF INNEWQDAVS KKTFPTVNPT TGEVIGHV - Ortholog sequence identity:
Mouse - 79%, Rat - 82%
Target Information
Aldehyde dehydrogenases (ALDHs) mediate NADP⁺-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde, lipid peroxidation, and metabolism of corticosteroids, biogenic amines, and neurotransmitters.
Alcohol drinking habits and cardiovascular disease risk factors may be associated with ALDH gene variants.
ALDH1B1 (Aldehyde dehydrogenase family 1 member B1), also known as ALDH5 or ALDHX (Aldehyde dehydrogenase X, mitochondrial), is a 517 amino acid mitochondrial protein expressed in liver, testis, and to a lesser extent in brain.
ALDH1B1 belongs to the aldehyde dehydrogenase family and may play a major role in ethanol detoxification.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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