Thermo Fisher Scientific Phospho-Acinus (Ser1180) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human Acinus (Phospho-Ser1180) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Acinus,uniProtId:Q9UKV3-1,ncbiNodeId:9606,antigenRange:1167-1190,antigenLength:1341,antigenImageFileName:PA5-64646_Acinus_Q9UKV3-1_Rabbit.svg,antigenImageFileNamePDP:PA5-64646_Acinus_Q9UKV3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2665123

Product Specific Information

Phospho-Acinus (Ser1180) Polyclonal Antibody detects endogenous levels of Acinus only when phosphorylated at Ser1180.

Target Information

ACINUS (apoptotic chromatin condensation inducer in the nucleus) is an induced of chromatin condensation. ACINUS is cleaved by caspase-3 and an additional unknown protease generating a small active peptide, p17, which causes chromatin condensation in vitro when it is added to purified nuclei. ACINUS also induces apoptotic chromatin condensation in cells. ACINUS is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.