ELK Biotechnology Histone H3 (Acetyl Lys14) rabbit pAb
Histone H3 (Acetyl Lys14) rabbit polyclonal antibody로 인간, 마우스, 랫트 시료에 반응합니다. WB, IF, ELISA에 적합하며, 핵 및 염색체 내 히스톤 구조 연구에 사용됩니다. 합성 펩타이드 항원으로 제작되어 높은 특이성과 재현성을 제공합니다.
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Histone H3 (Acetyl Lys14) rabbit pAb
공급업체: ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H3 (Acetyl Lys14) rabbit pAb |
| Alternative Names | HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3; H3k14AC |
| Applications | WB; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Histone H3 around the acetylated site of Lys14 (AA range: 1–50) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 19 kD |
| GeneID (Human) | 8350 / 8351 / 8352 / 8353 / 8354 / 8355 / 8356 / 8357 / 8358 / 8968 / 126961 / 333932 / 653604 / 3020 / 3021 |
| Human Swiss-Prot No | P68431 / Q71DI3 / P84243 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, forming higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone belonging to the histone H3 family. Transcripts from this gene lack polyA tails and contain a palindromic termination element. It is located in the large histone gene cluster on chromosome 6p22-p21.3. (RefSeq, Aug 2015)
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