ELK Biotechnology Cleaved-Caspase-2 p18 (T325) rabbit pAb
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| Product name: | Cleaved-Caspase-2 p18 (T325) rabbit pAb |
| Alternative Names: | CASP2; ICH1; NEDD2; Caspase-2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1 |
| Applications: | WB;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Caspase 2 p18 C-ternal. AA range:276-325 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 22kD |
| GeneID（Human）: | 835 |
| Human Swiss-Prot No: | P42575 |
| Cellular localization: | nucleus,cytoplasm,mitochondrion,cytosol,membrane, |
| Background: | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimers disease, Huntingtons disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011], |
| Species Reactivity: | Human;Mouse;Rat |
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