ELK Biotechnology CaMKIIβ/γ/δ rabbit pAb
CaMKIIβ/γ/δ 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간, 마우스, 랫, 돼지 반응성. 세포질 및 세포골격에 위치하며, 칼슘/칼모듈린 의존적 단백질 인산화 효소 연구에 적합.
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제품명
CaMKIIβ/γ/δ rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | CAMK2B; CAM2; CAMK2; CAMKB; Calcium/calmodulin-dependent protein kinase type II subunit beta; CaM kinase II subunit beta; CaMK-II subunit beta; CAMK2G; CAMK; CAMK-II; CAMKG; Calcium/calmodulin-dependent protein kinase type II subunit gamma |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CaMK2-beta/gamma/delta (AA range: 253–302) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 50 + 65 kD |
| Gene ID (Human) | 816 / 818 / 817 |
| Human Swiss-Prot No. | Q13554 / Q13555 / Q13557 |
| Cellular Localization | Cytoplasm, cytoskeleton; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome; Sarcoplasmic reticulum membrane (Peripheral membrane protein, Cytoplasmic side); Cell junction, synapse; In slow-twitch muscle, evenly distributed between longitudinal SR and junctional SR |
| Species Reactivity | Human; Mouse; Rat; Pig |
Background
The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants.
[Provided by RefSeq, May 2014]
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