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ELK Biotechnology Caldesmon (phospho Ser759) rabbit pAb
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Caldesmon 단백질의 Ser759 인산화 부위를 인식하는 토끼 폴리클로날 항체. IHC, IF, ELISA에 적합하며, 인간, 마우스, 랫트 시료에 반응. 세포골격 관련 단백질 연구에 유용. -20°C에서 장기 보관 가능.
- 판매단위
- pk
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ELK Biotechnology ES7604-100UL Caldesmon (phospho Ser759) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES7604-50UL Caldesmon (phospho Ser759) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology Caldesmon (phospho Ser759) rabbit pAb
Caldesmon (phospho Ser759) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | Caldesmon (phospho Ser759) rabbit pAb |
| Alternative Names | CALD1; CAD; CDM; Caldesmon; CDM |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | IHC: 1/100–1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Caldesmon around the phosphorylation site of Ser759 (AA range: 725–774) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 800 |
| Human Swiss-Prot No. | Q05682 |
| Cellular Localization | Cytoplasm, cytoskeleton, myofibril, stress fiber. On thin filaments in smooth muscle and on stress fibers in fibroblasts (nonmuscle). |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, serving as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
[provided by RefSeq, Jul 2008]
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