ELK Biotechnology GPR172A rabbit pAb
GPR172A rabbit pAb는 인간, 생쥐, 랫트에서 반응하는 다클론 항체로, 리보플라빈 수송 단백질을 검출합니다. WB, IF, ELISA에 사용 가능하며 고순도 IgG 형태로 제공됩니다. -20°C에서 1년간 안정적으로 보관됩니다.
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ELK Biotechnology GPR172A rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | GPR172A rabbit pAb |
| Alternative Names | SLC52A2; GPR172A; PAR1; RFT3; Solute carrier family 52; riboflavin transporter, member 2; Porcine endogenous retrovirus A receptor 1; PERV-A receptor 1; Protein GPR172A; Riboflavin transporter 3; hRFT3 |
| Applications | WB; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Antiserum produced against synthesized peptide derived from human PEVR1 (AA range: 43–92) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 46 kD |
| GeneID (Human) | 79581 |
| Human Swiss-Prot No | Q9HAB3 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene encodes a membrane protein belonging to the riboflavin transporter family. In humans, riboflavin must be obtained through intestinal absorption as it cannot be synthesized endogenously. Riboflavin is processed to coenzymes FMN and FAD, which act as intermediaries in many cellular metabolic reactions. Paralogous members of this family are located on chromosomes 17 and 20. Unlike other family members, this gene shows higher expression in brain tissue than in small intestine. Alternative splicing results in multiple transcript variants encoding the same protein. Mutations in this gene are associated with Brown-Vialetto-Van Laere syndrome 2, an autosomal recessive progressive neurologic disorder characterized by deafness and bulbar dysfunction.
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