ELK Biotechnology Tubulin α1/3/4 rabbit pAb
Tubulin α1/3/4 단백질을 인식하는 토끼 다클론 항체로, WB 및 ELISA에 적합합니다. 인간, 마우스, 랫트에 반응하며 세포질 및 세포골격에 위치한 단백질 검출에 유용합니다. 고순도 IgG, 1 mg/ml 농도, -20°C에서 1년 보관 가능합니다.
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ELK Biotechnology Tubulin α1/3/4 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Tubulin α1/3/4 rabbit pAb |
| Alternative Names | TUBA1A; TUBA3; Tubulin alpha-1A chain; Alpha-tubulin 3; Tubulin B-alpha-1; Tubulin alpha-3 chain; TUBA1B; Tubulin alpha-1B chain; Alpha-tubulin ubiquitous; Tubulin K-alpha-1; Tubulin alpha-ubiquitous chain; TUBA1C; TUBA6; Tubulin alpha-1C |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TUBA1/3/4 (AA range: 238-287) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 50–56 kD |
| Gene ID (Human) | 7846 / 10376 / 84790 / 113457 / 7278 / 112714 / 7277 |
| Human Swiss-Prot No. | Q71U36 / P68363 / Q9BQE3 / Q13748 / Q6PEY2 / P68366 |
| Cellular Localization | Cytoplasm, cytoskeleton |
| Species Reactivity | Human; Mouse; Rat |
Background
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which includes six distinct families. Genes from the alpha, beta, and gamma tubulin families are found in all eukaryotes. Alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.
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