ELK Biotechnology EFP rabbit pAb
TRIM25(EFP) 단백질을 인식하는 rabbit polyclonal antibody로 WB, IHC, IF, ELISA에 적합. 인간, 생쥐, 랫트 반응성. 세포질 및 핵에서 발현되는 EFP 단백질 연구에 활용 가능. 고순도 IgG, 1 mg/ml 농도, -20°C 보관.
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제품명
EFP rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | TRIM25; EFP; RNF147; ZNF147; E3 ubiquitin/ISG15 ligase TRIM25; Estrogen-responsive finger protein; RING finger protein 147; Tripartite motif-containing protein 25; Ubiquitin/ISG15-conjugating enzyme TRIM25; Zinc finger protein 147 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ZNF147 (AA range: 201–250) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 71 kD |
| GeneID (Human) | 7706 |
| Human Swiss-Prot No | Q14258 |
| Cellular Localization | Cytoplasm; Stress granule; Nucleus |
| Species Reactivity | Human; Rat; Mouse |
Background
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains (a RING, a B-box type 1, and a B-box type 2) and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen and is thought to mediate estrogen actions in breast cancer as a primary response gene. (provided by RefSeq, Jul 2008)
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