
ELK Biotechnology Vimentin (phospho Ser83) rabbit pAb
Vimentin 단백질의 Ser83 인산화 부위를 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 세포골격 연구 및 세포 이동, 신호전달 관련 연구에 적합. 사람, 생쥐, 랫트 반응성.
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Vimentin (phospho Ser83) rabbit pAb
제품 개요
Vimentin 단백질의 Ser83 인산화 부위를 인식하는 토끼 폴리클로날 항체입니다. 세포골격 유지, 세포 이동 및 신호전달 연구에 활용할 수 있습니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Vimentin (phospho Ser83) rabbit pAb |
| Alternative Names | VIM; Vimentin |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 ELISA: 1/10000 Other applications not yet tested |
| Immunogen | Synthesized peptide derived from human Vimentin around the phosphorylation site of Ser83 (AA range: 56–105) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 54 kD |
| Gene ID (Human) | 7431 |
| Human Swiss-Prot No. | P08670 |
| Cellular Localization | Cytoplasm; Cytoskeleton; Nucleus matrix; Cell membrane |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a member of the intermediate filament family. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene maintains cell shape, cytoplasmic integrity, and stabilizes cytoskeletal interactions. It also participates in immune responses and regulates LDL-derived cholesterol transport from lysosomes to esterification sites. Vimentin functions as an organizer of key proteins involved in attachment, migration, and cell signaling. Mutations in this gene can cause a dominant pulverulent cataract. (RefSeq, Jun 2009)
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