ELK Biotechnology Vimentin (phospho Tyr61) rabbit pAb
Vimentin (phospho Tyr61) rabbit pAb는 인산화된 Vimentin 단백질을 인식하는 폴리클로날 항체로, WB와 ELISA에 적합합니다. 세포 골격 연구에 활용되며, 인간·쥐·마우스 시료에서 반응합니다. 세포 구조 유지 및 신호전달 연구에 유용합니다.
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제품명
Vimentin (phospho Tyr61) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | VIM; Vimentin |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized phospho-peptide around the phosphorylation site of human Vimentin (phospho Tyr61) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 57 kD |
| Gene ID (Human) | 7431 |
| Human Swiss-Prot No. | P08670 |
| Cellular Localization | Cytoplasm; Cytoplasm, cytoskeleton; Nucleus matrix; Cell membrane |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene encodes a member of the intermediate filament family. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene cause a dominant, pulverulent cataract. [provided by RefSeq, Jun 2009]
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