
ELK Biotechnology UDP-GlcDH rabbit pAb
UDP-GlcDH rabbit pAb는 인간 UGDH 단백질을 인식하는 다클론 항체로, WB, IHC, IF, ELISA에 적합합니다. 1 mg/ml 농도로 제공되며, 핵 및 세포질 내 단백질 검출에 활용됩니다. UGDH 관련 세포 신호전달 및 암 연구에 유용합니다.
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제품명
UDP-GlcDH rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | UGDH; UDP-glucose 6-dehydrogenase; UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human UGDH (AA range: 391-440) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 55 kD |
| Gene ID (Human) | 7358 |
| Human Swiss-Prot No. | O60701 |
| Cellular Localization | Nucleus, nucleoplasm, cytosol, extracellular exosome |
| Species Reactivity | Human; Mouse; Rat |
Background
The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.
[provided by RefSeq, May 2010]
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