ELK Biotechnology Tuberin rabbit pAb
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| Product name: | Tuberin rabbit pAb |
| Alternative Names: | TSC2; TSC4; Tuberin; Tuberous sclerosis 2 protein |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Tuberin. AA range:947-996 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 210kD |
| GeneID（Human）: | 7249 |
| Human Swiss-Prot No: | P49815 |
| Cellular localization: | Cytoplasm. Membrane; Peripheral membrane protein. At steady state found in association with membranes. |
| Background: | Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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