
ELK Biotechnology C1q-C rabbit pAb
C1q-C rabbit pAb는 인간 C1QC 유래 펩타이드로 제작된 다클론 항체로, WB, IHC, IF, ELISA에 적합합니다. 보체 시스템의 C1q 구성요소 연구에 유용하며, 사람, 마우스, 랫트 시료에 반응합니다. -20°C에서 1년 보관 가능합니다.
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제품명
C1q-C rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | C1QC; C1QG; Complement C1q subcomponent subunit C |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 ELISA: 1/40000 Other applications not yet tested |
| Immunogen | Synthesized peptide derived from human C1QC (AA range: 81–130) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 30 kDa |
| Gene ID (Human) | 714 |
| Human Swiss-Prot No | P02747 |
| Cellular Localization | Secreted |
| Species Reactivity | Human, Mouse, Rat |
Background
This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s to form the first component of the serum complement system. Deficiency in C1q has been linked to lupus erythematosus and glomerulonephritis.
C1q consists of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain has a collagen-like region near the N-terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A–C–B on chromosome 1.
This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants encoding the same protein have been identified (RefSeq, Jul 2008).
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