ELK Biotechnology TTF-1 rabbit pAb
TTF-1 단백질을 인식하는 토끼 폴리클로날 항체로, Western Blot과 ELISA에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며 핵 내 단백질 검출에 유용합니다. -20°C에서 1년 보관 가능합니다.
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제품명
TTF-1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | NKX2-1; NKX2A; TITF1; TTF1; Homeobox protein Nkx-2.1; Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1; TTF-1 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/10000 Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TTF-1. AA range: 27–76 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 38 kD |
| Gene ID (Human) | 7080 |
| Human Swiss-Prot No. | P43699 |
| Cellular Localization | Nucleus |
| Species Reactivity | Human; Mouse; Rat |
제품 설명
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias TTF1 with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.
[provided by RefSeq, Feb 2014]
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