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ELK Biotechnology TRF1 (phospho Ser219) rabbit pAb
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TRF1 (phospho Ser219) rabbit pAb는 인간 텔로미어 반복 결합 인자 1의 인산화 부위를 인식하는 폴리클로날 항체입니다. WB 및 ELISA에 적합하며 핵 및 세포골격 내 단백질 검출에 사용됩니다. 고순도 IgG, 1 mg/ml 농도로 제공됩니다.
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- pk
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ELK Biotechnology ES7369-100UL TRF1 (phospho Ser219) rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES7369-50UL TRF1 (phospho Ser219) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology TRF1 (phospho Ser219) rabbit pAb
제품명
TRF1 (phospho Ser219) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | TERF1; PIN2; TRBF1; TRF; TRF1; Telomeric repeat-binding factor 1; NIMA-interacting protein 2; TTAGGG repeat-binding factor 1; Telomeric protein Pin2/TRF1 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Telomeric Repeat Binding Factor 1 around phosphorylation site of Ser219 (AA range: 185-234) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 55 kD |
| GeneID (Human) | 7013 |
| Human Swiss-Prot No. | P54274 |
| Cellular Localization | Nucleus; Cytoplasm, cytoskeleton, spindle; Chromosome, telomere. Colocalizes with telomeric DNA in interphase and prophase cells. Telomeric localization decreases in metaphase, anaphase and telophase. Associates with the mitotic spindle. |
| Species Reactivity | Human; Mouse |
Background
This gene encodes a telomere-specific protein that is a component of the telomere nucleoprotein complex. It is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit elongation of individual chromosome ends. The protein contains a C-terminal Myb motif, a dimerization domain near its N-terminus, and an acidic N-terminus. Two alternatively spliced transcripts are known.
[Provided by RefSeq, Jul 2008]
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