ELK Biotechnology TXA synthase rabbit pAb
TXA synthase rabbit pAb는 인간, 랫드, 마우스 시료에 반응하는 폴리클로날 항체입니다. Western blot과 ELISA에 사용 가능하며, C-말단 유래 펩타이드로부터 제작되었습니다. 약물 대사 및 혈소판 응집 관련 연구에 적합합니다.
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ELK Biotechnology TXA synthase rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | TXA synthase rabbit pAb |
| Alternative Names | TBXAS1; CYP5; CYP5A1; Thromboxane-A synthase; TXA synthase; TXS; Cytochrome P450 5A1 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/20000 Not yet tested in other applications. |
| Immunogen | Synthesized peptide derived from the C-terminal region of human TXA synthase. |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 60 kD |
| Gene ID (Human) | 6916 |
| Human Swiss-Prot No. | P24557 |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids.
However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity.
This endoplasmic reticulum membrane protein catalyzes the conversion of prostaglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation.
The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke.
Alternatively spliced transcript variants encoding different isoforms have been found for this gene. (Provided by RefSeq, Aug 2008)
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