ELK Biotechnology Syk (phospho Tyr352) rabbit pAb
Syk 단백질의 인산화 위치 Tyr352를 인식하는 rabbit polyclonal antibody로, WB와 ELISA에 적합합니다. 인간, 마우스, 랫트에 반응하며 세포막 및 세포질에 위치한 Syk 단백질을 검출합니다. 고순도 IgG, 1 mg/ml 농도로 제공됩니다.
- 판매단위
- pk
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제품명
Syk (phospho Tyr352) rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | SYK; Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized phospho-peptide around the phosphorylation site of human Syk (phospho Tyr352) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 72 kD |
| GeneID (Human) | 6850 |
| Human Swiss-Prot No | P43405 |
| Cellular Localization | Cell membrane; Cytoplasm, cytosol |
| Species Reactivity | Human; Mouse; Rat |
배경 (Background)
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
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