ELK Biotechnology SNAI 1 (phospho Ser246) rabbit pAb
SNAI1 단백질의 Ser246 인산화 부위를 인식하는 폴리클로날 토끼 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간, 마우스, 원숭이에 반응하며, 세포 내 핵 및 세포질에서 발현. -20°C에서 1년 보관 가능.
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제품명
SNAI 1 (phospho Ser246) rabbit pAb
대체 명칭
SNAI1; SNAH; Zinc finger protein SNAI1; Protein snail homolog 1; Protein sna
적용 분야 (Applications)
- Western Blot (WB)
- Immunohistochemistry (IHC)
- Immunofluorescence (IF)
- ELISA
권장 희석 배수 (Recommended Dilutions)
| Application | Dilution Range |
|---|---|
| Western Blot | 1/500 - 1/2000 |
| Immunohistochemistry | 1/100 - 1/300 |
| Immunofluorescence | 1/200 - 1/1000 |
| ELISA | 1/5000 |
| 기타 | Not yet tested in other applications |
면역원 (Immunogen)
The antiserum was produced against a synthesized peptide derived from human SNAI1 around the phosphorylation site of Ser246.
Amino acid range: 215–264
보관 조건 (Storage)
-20°C에서 1년 보관 가능
항체 정보
| 항목 | 내용 |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| 농도 (Concentration) | 1 mg/ml |
| Observed Band | 29 kDa |
유전자 정보
| 항목 | 내용 |
|---|---|
| Gene ID (Human) | 6615 |
| Human Swiss-Prot No. | O95863 |
세포 내 위치 (Cellular Localization)
Nucleus, Cytoplasm.
Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119), it is exported from the nucleus to the cytoplasm, where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs.
배경 (Background)
Snail family transcriptional repressor 1 (SNAI1) is a zinc finger transcriptional repressor that downregulates the expression of ectodermal genes within the mesoderm.
The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein and is thought to be critical for mesoderm formation during embryonic development.
At least two variants of a similar processed pseudogene have been found on chromosome 2.
[Provided by RefSeq, Jul 2008]
종 반응성 (Species Reactivity)
Human; Mouse; Monkey
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