
Thermo Fisher Scientific MRPL3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MRPL3. Validated for IHC (Paraffin) at 1:200–1:500 dilution. Antigen affinity purified, supplied in PBS with 40% glycerol. Suitable for mitochondrial ribosomal protein research. For research use only.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human MRPL3. Recombinant protein control fragment (Product # RP-106984) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662483 |
Product Specific Information
Immunogen sequence:
PGAVATGDIGR VWPGTKMPGK MGNIYRTEYG LKVWRINTKH NIIYVNGSVP GHKNCLVKVK DSKLPAYKDL GKNLPFPTYF PDGDEEELPE DLYDENVCQP GA
- Highest antigen sequence identity to orthologs: mouse 83%, rat 83%.
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are essential for protein synthesis within the mitochondrion.
Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with an estimated 75% protein to rRNA composition, opposite to prokaryotic ribosomes.
Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA.
The proteins comprising mitoribosomes vary significantly among species, hindering recognition by sequence homology.
This gene encodes a 39S subunit protein belonging to the L3P ribosomal protein family. A pseudogene corresponding to this gene is located on chromosome 13q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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