Thermo Fisher Scientific RPL14 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Immunogen sequence:
MVFRRFVEVG RVAYVSFGPH AGKLVAIVDV IDQNRALVDG PCTQVRRQAM PFKCMQLTDF ILKFPHSAHQ KYVRQAWQKA DINTKWAATR WAKKIEARER KAKMTDFDRF KVMKAKKMRN RIIKNEVKKL QKAALLKASP KKAPGTKGTA AAAAAAAAAK VPAKKITAAS KKAPAQKVPA QKATGQKAAP APKAQKGQKA PAQKAPAPKA SGKKA

Positive Samples: HL-60, HeLa, 293T, Jurkat, HepG2, Mouse ovary

Target Information

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.
This gene encodes a ribosomal protein that is a component of the 60S subunit and belongs to the L14E family of ribosomal proteins. It contains a basic region-leucine zipper (bZIP)-like domain and is located in the cytoplasm.
The gene contains a trinucleotide (GCT) repeat tract that results in a stretch of alanine residues in the encoded protein. Multiple transcript variants exist, all encoding the same protein.
As is typical for ribosomal protein genes, multiple processed pseudogenes are dispersed through the genome.

References:
Aoki M., Diabetes 45:157–164 (1996).
Tanaka M., Biochem. Biophys. Res. Commun. 243:531–537 (1998).
Yoshihama M., Genome Res. 12:379–390 (2002).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.