Thermo Fisher Scientific CML Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:20,000

-

ELISA (ELISA)

1:1,000-1:20,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CML-KLH.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

75mM sodium phosphate/PBS, pH 7.2, with 0.5mM EDTA

Contains

0.02% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Carboxymethyl-lysine (CML) is a modified amino acid derivative that is formed during the Maillard reaction, a chemical reaction between amino acids and reducing sugars. Structurally, CML is formed by the addition of a carboxymethyl group to the lysine residue in proteins. The purpose of studying CML lies in its potential role as a biomarker for oxidative stress and the development of chronic diseases, such as diabetes, cardiovascular diseases, and aging-related conditions. Additionally, CML has been implicated in the pathogenesis of diabetic complications, such as nephropathy and retinopathy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.