Thermo Fisher Scientific PHF23 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PHF23. Recombinant protein control fragment (Product #RP-93167). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PHF23,uniProtId:Q9BUL5-1,ncbiNodeId:9606,antigenRange:262-348,antigenLength:403,antigenImageFileName:PA5-62603_PHF23_Q9BUL5-1_Rabbit.svg,antigenImageFileNamePDP:PA5-62603_PHF23_Q9BUL5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2645494

Product Specific Information

Immunogen sequence: MATVVGGEAP VPVLPTPPEA PRPPATVHPE GVPPADSESK EVGSTETSQD GDASSSEGEM RVMDEDIMVE SGDDSWDLIT CYCRKPF

Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 84%.

Target Information

Acts as a negative regulator of autophagy, through promoting ubiquitination and degradation of LRSAM1, an E3 ubiquitin ligase that promotes autophagy in response to starvation or infecting bacteria.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.