Thermo Fisher Scientific CellSensor NFAT-bla RA-1 Cell Line
B세포 수용체(BCR) 신호 경로 연구용 CellSensor NFAT-bla RA-1 세포주. SYK, PKC, 칼슘 경로 등 신호 전달 분석에 적합. 형광 기반 베타 락타메이스 리포터 어세이로 검증 완료된 스크리닝용 세포주.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Thermo Fisher Scientific CellSensor™ NFAT-bla RA-1 Cell Line
B cell receptor (BCR)-mediated signaling pathways are crucial for B cell proliferation and differentiation. Abnormal B cell signaling has been linked to diseases such as lupus, lymphoma, and various immune disorders.
Antigen binding to the BCR activates several protein tyrosine kinases (PTKs), leading to phosphorylation of the BCR complex and recruitment of the PTK Syk. This promotes phosphorylation of PLCγ, Shc, and Vav. Additionally, the Tec family member Btk is recruited to the plasma membrane and participates in PLCγ activation.
Initiation of B lymphocyte activation depends on tyrosine phosphorylation-dependent formation of multimolecular effector protein complexes that activate downstream signaling pathways, including PKC/Ca²⁺/NFAT.
This cell-based assay has been thoroughly tested and validated by Invitrogen and is suitable for immediate use in screening applications. The following information illustrates the comprehensive assay testing completed and validation of assay performance under optimized conditions.
제품 사양
| 항목 | 내용 |
|---|---|
| 어세이 입력 | Cell-based beta lactamase reporter gene |
| 셀 상태 | Dividing Cells |
| 검출 방법 | Fluorescence |
| 제품 라인 | CellSensor™ |
| 수량 | 1 Vial |
| 타겟 입력 | SYK, PKC and calcium pathway, BTK |
| 유형 | Cell Line |
| 세포주 | RA-1 |
| System Type | CellSensor™ |
| Druggable Target | Signaling Pathway |
| Unit Size | Each |
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific GeneBLAzer EDG7-NFAT-bla HEK 293T Cells
25,903,800원
Thermo Fisher Scientific
Thermo Fisher Scientific CellSensor TrkA-NFAT-bla CHO-K1 Cell Line
18,149,300원
Thermo Fisher Scientific
Thermo Fisher Scientific CellSensor NFAT-bla RA-1 Cell Line
17,897,500원
Thermo Fisher Scientific
Thermo Fisher Scientific Tango HRH3-bla U2OS DA Assay Kit
1,466,300원
Thermo Fisher Scientific
Thermo Fisher Scientific LanthaScreen STAT3 GripTite Cell Line
17,897,500원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|