Thermo Fisher Scientific Human NIPSNAP3A Synthetic Peptide

Applications

Control (Ctrl)

• Assay-dependent

Blocking Assay (BLOCK)

• Assay-dependent

Product Specifications

Product Specific Information

This peptide corresponds to 16 amino acids near the center of human NIPSNAP3A.
PEP-0777 can be used as a blocking peptide with polyclonal antibody PA5-20657.

Target Information

The NIPSNAP proteins comprise a family of evolutionarily well-conserved proteins with strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein.
NIPSNAP2, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumors.
While NIPSNAP3B is highly expressed in skeletal muscle, NIPSNAP3A mRNA levels are low. NIPSNAP3A protein is associated with plasma membrane and partially localized in rafts.
NIPSNAP proteins have been suggested to be important in vesicular transport.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.