ELK Biotechnology VPS18 rabbit pAb
VPS18 단백질을 인식하는 토끼 폴리클로날 항체로, WB에 적합하며 인간 및 생쥐 시료에 반응합니다. 합성 펩타이드 면역원으로 제작되었으며, -20°C에서 1년 보관 가능합니다. 세포 내 소낭 단백질 연구에 활용됩니다.
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제품명
VPS18 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human VPS18 (AA range: 778–828) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 57617 |
| Human Swiss-Prot No. | Q9P253 |
| Species Reactivity | Human, Mouse |
세포 내 위치
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome. Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle, clathrin-coated vesicle. Cytoplasmic, peripheral membrane protein associated with early endosomes and late endosomes/lysosomes.
Background
Vesicle-mediated protein sorting plays an important role in the segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps18 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. [provided by RefSeq, Jul 2008]
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